By Masataka Nakano M.D., Jacob Stephen M.D., Miranda C. A. Kramer M.D. (auth.), Allen J. Taylor, Todd C. Villines (eds.)
Atherosclerosis: medical views via Imaging is aimed toward working towards clinicians and depends upon didactic tabular and bullet issues and a bunch of good imagery describing the typical beneficial properties of the imaging of atherosclerosis, allowing the reader to appreciate extra concerning the merits and barriers of every modality in investigating athersclosis. Edited by way of and contributed to via a number of foreign specialists in cardiac imaging, this booklet is a needs to learn through all who photograph the heart.
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Extra resources for Atherosclerosis: Clinical Perspectives Through Imaging
2003;289:2560. 13. Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics 2011 update: a report from the American Heart Association. Circulation. 2011;123:e18–209. 14. Kannel WB, McGee DL. Diabetes and glucose tolerance as risk factors for cardiovascular disease: the Framingham Study. Diabetes Care. 1979;2:120–6. 15. Haffner SM, Lehto S, Rönnemaa T, Pyörälä K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction.
Physical Inactivity • Physical inactivity is a minor modifiable risk factor for coronary heart disease, and regular exercise has been shown to reduce risk for CHD in a number of observational epidemiological studies [1, 3, 28]. • The mechanisms for this apparent benefit are multi-factorial and may include an increase in HDL cholesterol and a decrease in bodyweight, insulin resistance, and blood pressure. • Participants of the Honolulu Heart Study who reported the highest tertile of physical activity index showed a 26 % reduction in 23-year coronary heart disease mortality after adjusting for age  (Fig.
Although low HDL cholesterol is known to be a risk factor for CHD and treatment with medications to increase HDL leads to atherosclerosis regression, the large federally funded AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides) trial was stopped early because the addition of niacin to a statin did not reduce the risk of cardiovascular events . Due to a number of important trial design limitations and the limited power and duration of the trial, definitive understanding of the impact of niacin on clinical cardiovascular outcomes awaits further investigation.