By P. B. Persson (auth.), Dr. med. P. B. Persson, Prof. Dr. med. H. R. Kirchheim (eds.)
It is a smart honor and enjoyment for me to introduce this booklet; an honor, due to the clinical renown and authority of the investigators who've edited the quantity and contributed the chapters; a excitement, simply because my very own long-lasting curiosity within the baroreflexes has consistently long past within the similar instructions as these alongside which the authors of this publication have conceived and arranged their paintings. it truly is rather significant, for my part, that the very identify of this quantity underlines the integrative capabilities and the scientific facets of baroreceptor reflexes. lower than the point of integration, it's progressively more obvious that baroreceptor reflexes, even though preponderantly influencing cardiovascular features, are usually not restricted to cardiovascular keep an eye on. Their impression on respiratory has been renowned because the earliest experiences on baroreflexes, and wider impacts have extra lately been proven, e. g. , on hormone unlock, on sleep and vigilance, and on emotional habit. Even in the scope of cardiovascular legislation, the built-in motion of baroreflexes isn't just without delay exerted at the middle and blood vessels, yet is usually exerted via extra devious yet no less significant routes, reminiscent of renin liberate from juxtaglomerular cells and sodium and water reabsorption by way of the renal tubules.
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Additional info for Baroreceptor Reflexes: Integrative Functions and Clinical Aspects
In: Berne RM, Sperelakis N, Geiger SR (eds) The heart. American Physiological Society, Bethesda, pp 621-652 (The cardiovascular system, sect 2, vol 1) 40. Ead HW, Green, JH, Neil E (1952) A comparison of the effects of ptdsatile and non-pulsatile flow through the carotid sinus on the reflexogenic activity of the sinus receptors in the cat. J Physiol (Lond) 118:509-519 41. Eyzaguirre C, Uchizono K (1961) Observations on the fiber content of nerves reaching the carotid body of the cat. J Physiol (Lond) 159:268-281 42.
More recent studies have shown Baroreceptor Discharge Behavior and Resetting 39 acute or rapid resetting of baroreceptors within 5-20 min of a change in conditioning pressure. In contrast to chronic resetting, acute resetting is characterized by an increase in threshold pressure and no change in the gain of the pressure-nerve activity curve. Despite numerous studies, the mechanism of acute resetting remains controversial and elusive. However, recent studies indicate that pulsatile pressure prevents acute resetting, provided the sympathetic innervation to the receptors remains intact.
And DOCA hypertension in the rat. Cardiovasc Med 2:761-766 29. Davis 10 (1977) The pathogenesis of chronic renovascular hypertension. Circ Res 40:439-444 30. DeCastro F (1928) Sur la structure et l'innervation du sinus carotidien de l'homme des mammiferes: nouveaux faits sur l'innervation et a fonction du glomus caroticum. Etudes anatomiques et physiologiques. Trab Lab Invest BioI Madrid 25:331-380 31. DeCastro F (1951) Sur la structure de la synapse dans Ie chemorecepteurs: leur mechanisme d'excitation et role dans la circulation sanguine locale.