By c waddington
Organic corporation - mobile AND SUB-CELLULAR.
Proceedings of a Symposium organised on behalf of UNESCO via C. H. Waddington, held on the collage of Edinburgh, Scotland, September, 1957.
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Additional info for Biological Organisation: Cellular and sub-cellular.
Most morphological products are not established by sponall at once, but evolve along a time line, that means that it is going to be possible, and increasingly so, to reduce or resolve space patterns to orderly sequences of processes. Just where this breaks Now, since taneous generation down is an empirical question of* the future. Just as the orderliness of an assembly can often be referred to the orderly aggregation of the units, so order of form can arise from the order of the formative processes.
Then, we have also to consider the two antagonising groups of factors which are in all structural levels (inside the cells, in cell populations, in different organs) always interlinked, on the one side the inhibiting, on We recall here the regulation of the other side the activating, factors. enzyme activities by metabolite controlled feed-back mechanisms, and the induction of enzyme activity by some substrates. Then, on different levels and in many cases there are very interesting threshold effects, where with a given intensity of action the processes are guided in one way and with another intensity they will take a qualitatively different direction.
Of course, as you all know, a hot favourite for this material is DNA. Now, you may DNA being the genetic carrier, and most of the based on microbiological studies; and you may ask whether experiments with micro-organisms have any bearing on experiments with higher animals. What I'd like to show, in a quite speculative way, is how they have a bearing on organisms which have a higher degree of ask for the evidence for evidence is organisation. I shall not go into the evidence I take it that we all know the evidence on which we base the idea that DNA carries what we like to call genetic What we should like to understand is exactly how genetic information gets transferred to the rest of the cell.