By Michael W. Shannon MD MPH FAAP FACEP FAACT FACMT, Stephen W. Borron MD MS FACEP FACMT, Michael Burns MD
The fourth version of Haddad and Winchester's scientific administration of Poisoning and Drug Overdose is the most up-tp-date, authoritative, and concise reference for info concerning the medical administration of kids and adults whose overall healthiness has been effected or possibly effected through poisonous brokers, together with medications, environmental threats, and ordinary toxins.Presents a finished remedy of poisoning via greater than a hundred chapters in 10 sectionsTemplated layout presents key details in a layout that's effortless to discover and understandInternational authorship, permitting textual content to handle concerns globally as poisoning and drug overdose are world wide issuesPresents a beautiful full-color layout that's crucial for settling on environmental toxinsNew chapters on occupational and environmental toxicologyExpanded sections on bioterrorismAdded 3 editors who're toxicologists and altered editors for person chapters
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The fourth version of Haddad and Winchester's medical administration of Poisoning and Drug Overdose is the most up-tp-date, authoritative, and concise reference for info regarding the medical administration of youngsters and adults whose wellbeing and fitness has been effected or possibly effected by way of poisonous brokers, together with medicinal drugs, environmental threats, and typical pollutants.
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Extra info for Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose, 4th Edition
Glucagon Glucagon is a single-chain pancreatic polypeptide that is an effective inotropic and chronotropic agent. Its mechanism of action is direct stimulation of myocardial glucagon receptors; these receptors, when stimulated, increase the formation of myocardial cAMP. The resultant effect is positive inotropy and, to a lesser degree, positive chronotropy. Glucagon is theoretically most effective after β blocker overdose, in which decreased β-adrenergic receptor activation leads to diminished cAMP production.
Repeated assessment, especially of vital signs and of cardiac, pulmonary, and neurologic status, is critical to proper management of the toxicologic patient. The physical examination also can provide valuable clues as to the particular toxin involved (Table 2A-6). Vital Signs As part of the initial evaluation, complete determination of vital signs, including measurement of body temperature initially and throughout the emergency department assessment, is mandatory. Obtaining a core body temperature measurement may be necessary.
Again, if the agent is known to have signiﬁcant dermal absorption, emergency medical personnel should provide themselves every available level of self-protection. Certain toxins such as organophosphates can contaminate the air within the ambulance and produce ill effects among personnel if prehospital decontamination efforts are inadequate. Upon arrival at a health care facility, the victim may require quarantine, depending on the nature of the agent. Skin decontamination in a decontamination shower should continue.