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Extra info for Neurochemistry: Cellular, Molecular, and Clinical Aspects
Tocopherol and Vitamin C) before and following CHI will help to resolve this issue. In conclusion the present animal model studies suggest that apoE plays an important role in neuronal repair and that these neuroprotective effects may be due, at least in part, to apoE related antioxidative mechanisms. Further identification of the specific brain antioxidants whose levels are affected by apoE in conjunction with in vitro studies of the antioxidative capacity of distinct apoE isoforms are expected to contribute to our understanding of the role of antioxidative mechanisms in the neuroprotective capacity of apoE both in model systems and in AD.
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674: 55--62. , 1984,1. Neurosci. Meth. 11: 47--60. , 1993,1. Pharmacol. & Toxicol. Methods 29: 485-493. , Horwitz, M. , 1995, J. Cereb. Blood Flow and Metabolism 15, Supp;. I, S713. Section 2: New Aspects of Alzheimer's and Other Neurodegenerative Diseases 5 THE ROLE OF CYTOKINES IN ALZHEIMER'S DISEASE M. Hull,' B. L. Fiebich,1 K. Lieb,' B. Volk,2 M. Berger, and 1. Bauer 'Department of Psychiatry 2Department of Neuropathology Medical School, University of Freiburg, Freiburg 1. ACUTE PHASE PROTEINS ARE PRESENT IN THE BRAINS OF ALZHEIMER'S DISEASE PATIENTS In Alzheimer's disease (AD), acute-phase proteins such as a,-antichymotrypsin (1,2), ai-antitrypsin (3,4), apolipoproteins (5-7), C-reactive-protein (8) and the adhesion molecule ICAM-I (9,10) have been found in cerebral amyloid plaques.